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Adicionalmente, la sibutramina produce un aumento de la frecuencia cardiaca y la presin sangunea, que pueden ser clnicamente significativas en algunos pacientes, habindose registrado casos de arritmias, cardiopatas isqumicas y accidentes vasculares graves con su consumo

Attempts have also been made to create redox and pH-sensitive nanogels for the rapid release of DOX to triple-negative breast cancer cells 80

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