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[DOI] [PubMed] [Google Scholar] Garca Muoz R, Izquierdo-Gil A, Muoz A, Roldan-Galiacho V, Rabasa P, Panizo C, 2014

This effect exerted was found to be mediated by the subsequent activation of the PI3K/Akt/GSK3 signaling pathway, followed by the activation of IP3R in the endoplasmic reticulum that resulted in the elevation of intracytoplasmic Ca 2+ , which finally culminated in mitochondria-dependent apoptosis

Frozen-then-thawed glutathione is worse than oxidised glutathione because structural damage prevents any residual antioxidant function

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