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Mean body weight reduction was 14.9% in the semaglutide group versus 2.4% in placebo

HT1080-HMGB1-Lucia cells stably express an HMGB1::Lucia luciferase fusion protein in the cytoplasm, in which the C-terminus of the High-Mobility-Group-Protein B1 (HMGB1) is fused to the Lucia luciferase

Funciona como un agonista del receptor de GLP-1, lo que significa que ayuda a controlar el apetito y a reducir la ingesta de caloras

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The study demonstrated that ketone body levels can serve as sensitive metabolic indicators for insulin resistance and fatty acid oxidation efficiency in metabolic disease research