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J Cosmet Dermatol 22(11):30883094

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Studies in laboratory animals confirm the etiological role of cytokines in liver damage in ALD, with elevated levels of tumor necrosis factor alpha (TNF-) and TNF--induced cytokines/chemokines such as interleukins (IL) -6, 8 or 18, and that the levels of these cytokines correlate with markers of the acute phase response, liver function and the clinical picture of the disease (66)