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[DOI] [PubMed] [Google Scholar] 2.Kamakshi R

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Diabetic painful neuropathy has been shown to be mediated via an inflammatory chemokine pathway (23) and strategies to reduce this inflammation, including gene transfer of soluble TNF receptor, have been shown to alleviate pain (24)

A 1 mg dose draws 0.2 mL (20 units on a U-100 syringe), and a 0.5 mg dose draws 0.1 mL (10 units)

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Older work characterized DSIP as a sleep-modulating peptide rather than a sedative, with a U-shaped activity curve where small doses or short infusions produced the strongest effect