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Ethics declarations Competing interests C.J.H.P., N.L.T

Formulations may vary based on provider recommendations and individual patient needs

First, it is important to remember that plateaus with GLP-1s are different from the stalls you might have experienced while trying to lose weight without medication

It works by mimicking the natural gut hormones GLP-1 and GIP to regulate appetite, digestion, and blood sugar to promote weight loss

The conversation about what to say when requesting GLP-1 options from your provider can make a significant difference in the alternatives presented to you

There isnt good scientific evidence to show that theyre safe or effective in that space. Online chatter has conflated microdosing with being harmless suggesting its a little dose, or its not like taking a medication at all, Crotty says