They do this by inhibiting the production of prostaglandins that protect the stomach wall from its own acid
The exact underlying mechanisms arent fully settled (and we need future studies), but there are a few strong theories at a cellular level that line up with what we see clinically
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The activities and levels of multiple cellular effectors involved in the regulation of cell death, including caspase-3, caspase-9, and cytochrome C, indicate that cells die in individuals with PD, 230,231 which has also been proven by the number of TUNEL-positive cells and in situ DNA fragmentation
Thats the exact scenario Retatrutide creates