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Patients with poorly controlled diabetes may have increased infection susceptibility and should maintain heightened vigilance

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Abstract Classical metabolomic and new metabolic network methods were used to study the developmental features of autism spectrum disorder (ASD) in newborns ( n = 205) and 5-year-old children ( n = 53)

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Following FOXO4 displacement, the released p53 undergoes nuclear export and mitochondrial translocation, activating the intrinsic apoptosis pathway via BAX upregulation and BCL-2 downregulation, culminating in caspase-3 cleavage and apoptotic cell death