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Among the newly synthesized analogs, compounds 3 and 4 (Figure 7) demonstrated superior anti-inflammatory properties and caused fewer gastric ulcers compared to celecoxib

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In addition, folic acid therapy, at 400 mcg (680 mcg DFE) twice daily for three months, increased sperm concentrations more in those with the MTHFR 677 TT genotype (version of the gene) than those with the more prevalent MTHFR 677 CT or MTHFR 677 CC genotypes

Wu H, Lu Z, Chen R, Cai Q, Wang M, Zhang L, et al

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These principles can be reasonably extended to agar-based systems through appropriate surface engineering strategies