For cohort 1, the ODB database was used to identify patients who were prescribed vitamin B12 injections
Br J Pharmacol 2021;178:2569-94
Multiple clinical trials show that FMT is superior to placebo for inducing clinical remission in active UC (Paramsothy et al., 2019), although outcomes are influenced by donor selection, delivery route, and the patient's baseline microbiota (Pinto et al., 2025)
Additional booster infusions may be scheduled based on lab results, nicotinamide/NAD+ levels, hormone panels, or cycle tracking
A low of 6 variable region peptides were observed from HLA-DRB1*12:01 and a high of 100 variable region peptides were observed from HLA-DRB1*01:01 (Supplementary Data S1)
doi: 10.1016/j.cell.2024.07.041 186