Meanwhile, GLP-1 receptor activation links with neurotrophic effects, including neurogenesis and neuroprotective effects, including reduced necrotic and apoptotic signaling, cell death, and dysfunctions
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In further support of this notion, GLP-1R agonists can still reduce food intake when the aversive pathways of the AP are inhibited
GLP-1RA users showed greater weight loss, lower knee surgery incidence, reduced pain, slower cartilage loss compared to the control group