While glutathione synthesis is controlled by multiple factors, GCL is the main determinant, because the rate-limiting step is the cellular level of the amino acid cysteine
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Enhancement of human monocyte and peritoneal macrophage chemiluminescence activities in women with endometriosis
Gaidamauskas E, Gyrup C, Boldt HB, Schack VR, Overgaard MT, Laursen LS, Oxvig C.IGF dependent modulation of IGF binding protein (IGFBP) proteolysis by pregnancy-associated plasma protein-A (PAPP-A): multiple PAPP-A-IGFBP interaction sites