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CREATINE C TC DNG G

Preclinical studies found that treating neuronal, nematode, or rodent AD models with NR resulted in induction of a mitochondrial stress response, including UPR mt and mitophagy, reduced proteotoxic stress, and decreased A accumulation 243

Some trial participants showed total body weight reductions in the 20-25% range, though these figures come from smaller, shorter studies and should be interpreted with caution until phase 3 data is published

Luk et al., 2015)

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