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Express Scripts requires BMI of 30 or higher, or BMI of 27 or higher with at least one weight-related comorbidity (type 2 diabetes, hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease)

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The evidence base now supports both short-term weight loss and long-term metabolic improvement

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Microbiome, trimethylamine N-oxide, and cardiometabolic disease

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doi: 10.1016/j.jcmgh.2015.08.007 227

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Without enough vitamin B12, homocysteine can build up

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