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For example, engineered Escherichia coli Nissle 1917 (EcN) co-expressing anti-PD-L1 and anti-CD9 nanobodies (EcN-Nb) and modified with ICG-loaded zinc-based MOFs to generate EcN-Nb-ZIF-8CHO-ICG (ENZC), can specifically release nanobodies in response to NIR radiation thereby targeting tumor-derived exosomes (TDEs) to alleviate immunosuppression, such as reshaping TAMs to the M1 state and activating more effective and cytotoxic T lymphocytes, ultimately inhibiting tumor proliferation and metastasis (229)

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When we manage our health, we feel more in control

Autoimmune conditions: Some autoimmune diseases, like celiac disease or inflammatory bowel disease, can impact DAO production and gut health

We identified an increase of possible signaling modules (3-HB and 2-oxoglutarate) during fasting

This proactive approach empowers you to sustain a consistently balanced, healthy lifestyle