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Identification of bioactive metabolites using activity metabolomics

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Sands BE, Sandborn WJ, Panaccione R, OBrien CD, Zhang H, Johanns J, et al

Cancer Lett 115(2):129133 Fleischauer AT, Arab L (2001) Garlic and cancer: a critical review of the epidemiologic literature

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Research Protocol Summary Study Protocol: 0.25 mg AOD-9604 administered intra-articularly via ultrasound guidance Frequency: Weekly injections Duration: 4-7 weeks in research studies Combination Therapy: 6 mg hyaluronic acid co-administered for enhanced effects Assessment Timeline: Significant improvements observed by 8-9 weeks Note: These protocols are from animal research and have not been validated for human use