Semaglutide The SUSTAIN-6 (trial to evaluate cardiovascular and other long-term outcomes with semaglutide in subjects with type 2 diabetes) was a double-blind trial in which T2D patients were randomized to receive either 0.5 or 1.0 mg of once-weekly subcutaneous semaglutide or placebo (Marso et al., 2016a)
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Results are limited by the relatively small sample size and the sub-optimal number of band-adjustments which is, in part, related to the COVID pandemic and may underpin the sub-optimal weight and glycaemic responses in both groups
[DOI] [PubMed] [Google Scholar] 50.Toto M., Margari F., Simone M., Craig F., Petruzzelli M.G., Tafuri S., Margari L
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Binding of paracetamol metabolites to mouse liver glutathione S-transferases