Hygroscopic, Refrigerator, under inert atmosphere solubility DMSO (Slightly), Methanol (Slightly) form Solid pka 9.830.15(Predicted) color White to Off-White Sequence Hexanoyl-Tyr-Ile-Ahx-NH2 InChIKey ADWKPLXLPNPJTR-JTJYXVOQSA-N SMILES C(N)(=O)[C@H]([C@@H](C)CC)N(C(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)CCCCC)CCCCCC(N)=O Description Dihexa (developmental code name PNB-0408), also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met
Chemosphere Developmental toxicity assessments for TBBPA and its commonly used analogs with a human embryonic stem cell liver differentiation model
Preclinical investigations have examined Dihexa in the following mechanistic areas: Potentiation of HGF-dependent c-Met phosphorylation and cellular scattering Induction of synaptogenesis and dendritic arborization in neuronal models Examination of signaling pathway activity in cognitive impairment paradigm models Investigation of neuroplasticity markers in experimental stress or aging paradigm models Study of neuronal survival pathway signaling in neurodegenerative research contexts Why Researchers Choose Our Dihexa For laboratories requiring dependable Dihexa research peptide, our manufacturing process prioritizes reproducibility and scientific precision
Pharmacokinetic parameters after intravenous administration in rats showed Dihexa possessed a long half-life of 12.68 days and was extensively distributed, indicated by a large volume of distribution (Va)
Frequently Asked Questions What is Dihexa
Every batch of Dihexa undergoes rigorous third-party analytical testing (including HPLC and Mass Spectrometry) to verify minimum 99%+ purity, exact molecular weight (504.67 g/mol), and complete absence of unreacted synthetic fragments or heavy metals
