It needs careful thought about what the patient needs and what the treatment aims to achieve
People with digestive or absorption issues : As mentioned, conditions like Crohns disease, IBS, or celiac disease can prevent proper absorption of B12 making injections the best option for getting enough of the nutrient
Generally, its difficult to say precisely how long a vitamin B12 shot lasts in the body
Another study in the Journal of the American Medical Association notes that among those with diabetic nephropathy (loss of kidney function due to diabetes), combining vitamin B6 (25 mg) and folic acid (2.5 mg) (B-complex vitamin) with 1,000 mcg of oral B12 per day for six years increases the risk of cardiovascular events, including heart attack and stroke
Some may also experience constipation, leading to an inability to absorb nutrients, or a sluggish metabolism
M., Wolffenbuttel, B