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For the global metabolite profiling in serum, the metabolites in 10 L of serum were extracted by the 390 L of pre-chilled 82% MeOH (80 C) followed by 15 min incubation at 80 C

[21] Although the liver is capable of glutamine synthesis, its role in glutamine metabolism is more regulatory than productive, as the liver takes up glutamine derived from the gut via the hepatic portal system

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Martin BD, Finke RG

These findings indicate that ferroptosis is a novel therapeutic target for treating glaucoma, especially in addressing the ongoing RGC loss following ph-IOP control [324]

Elife (2022) 11:e76095