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Berberine is an alkaloid that can be found in a number of plants, including rhizome, European barberry, Oregon grape, and others

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Moreover, evidence supporting EGCGs neuroprotective effects via BBB-mediated anti-neuroinflammation and reduction of oxidative stress includes: (i) EGCG enhances dopamine neuron activity in the gut, decreases serotonin levels in the colon, and increases hippocampal 5-hydroxytryptamine levels by enhancing intestinal permeability (215217)

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