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Corticotropin-releasing factor: actions on the sympathetic nervous system and metabolism
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JAMA 334(9):822823
In immortalised human airway epithelial cell lines (including bronchial epithelial cells) and human alveolar epitheliallike cells, GLP-1 receptor agonists reduced epithelial stress and inflammatory signalling, including downregulation of epithelial-derived cytokines, including IL-33 and thymic stromal lymphopoietin (TSLP), both of which are implicated in epithelialmesenchymal crosstalk and fibroblast recruitment in fibrotic lung disease [66,67,68]
Shiling's nasal spray is designed for long-term use and offers a lower cost compared to semaglutide tablets, according to a statement provided to Reuters on February 10