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Smits MM, Van Raalte DH

Additional research is required to ascertain the variability in the risk of biliary diseases associated with GLP-1 RAs

Retatrutide Starts at $375* Retatrutide is an advanced triple-action metabolic therapy designed to support significant weight loss, optimize metabolic function, and enhance overall energy balance by targeting GLP-1, GIP, and glucagon pathways

Diabetes Ther (2019) 10:519

The diabetes-specific TRANSCEND-T2D-1 population tolerated it better (5.1%)

The drugs currently cost about $1,000 per months supply, or about half that amount if patients obtain them directly from the companies through newly launched direct-to-consumer programs