Consuming foods high in sulfur, such as garlic, onions, broccoli, and cruciferous vegetables, can support the body's natural glutathione synthesis
Additionally, the nuclear export signal (NES) in KEAP1 has been shown to be important for NRF2 regulation, as it was found to facilitate the transport of the NRF2-KEAP1 complex out of the nucleus, which terminates NRF2-mediated antioxidant signaling after stress [16]
Gac Sanit 35(Suppl 2):S196S198 Alam MA, Roy S, Rahman MA, Islam MR, Rahman MM, Obaidullah AJ, Farid MN, Rahman MM, Islam MR, Mozumder SN, Almalki RS, Gaber A, Hossain A (2024) Study on the genetic variability and adaptability of turmeric ( Curcuma longa L.) genotypes for development of desirable cultivars
Likewise, the mRNA of inflammatory mediators (iNOS, IL-6, IFN and TNF-) are inhibited, with increased expression of HSP 70 and 90, and antioxidant proteins, such as HO-1, NQO-1, glutathione reductase, glutathione peroxidase 2 and GST-pi [19]
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