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Slowed gastric emptying: By delaying stomach emptying, GLP-1 RAs increase feelings of fullness and reduce meal size

GLP-1(736) and exenatide activated GLP-1Rs expressed on microglial cells in the spinal dorsal horn, which were significantly upregulated following peripheral nerve injury

No cases of pancreatitis, thyroid C-cell tumours, or severe hypoglycaemia were reported in the Phase 2 cohort

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PubMed Lou FQ, Zhang MF, Zhang XG, et al