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In einem Bleomycin-induzierten Fibrosemodell reduzierte die GHK-Behandlung die Infiltration von Entzuendungszellen und die interstitielle Verdickung bei gleichzeitiger Senkung von TNF-alpha und IL-6

In mice, infarction was induced by coronary artery ligation and a single dose of oral hexarelin was administered 30 minutes after surgery

Cell Metab 21:739746

Research protocols typically use daily dosing for 714 days during the induction phase, with therapeutic effects lasting 30+ days post-treatment despite complete plasma clearance within 12 hours of the final dose

Key sites include the liver, adipose tissue, lactating mammary glands, adrenal cortex, and red blood cells, which require NADPH to preserve membrane integrity.

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