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[2] Sigalos JT, Pastuszak AW, Allison A, et al

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Bothersome Symptoms The following are symptoms, and their causes, which can be bothersome: Need to urinate often during the day and night (called nocturia) is a first symptom

[1] Additionally, the authors indicate that there is still a requirement for successful human trials to be completed prior to clinical translation as there are important differences between rodent and human physiology that could have a significant impact on the efficacy and safety of any agent

Contraindications include active infection at the injection site, severe thrombocytopenia, or anticoagulation therapy requiring provider clearance