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The liver metabolizes alcohol at an average rate of one standard drink per hour

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These agents target multiple hormone pathways involved in appetite regulation, insulin secretion, energy expenditure, and hepatic metabolism

Mounting evidence indicates that both disease biology and drug responsiveness in MASH and fibrosis are sexually dimorphic: pre-menopausal women exhibit slower fibrosis progression but may respond differently to metabolic therapies [55, 60, 61]