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10.1038/nm.3761 201

His team forecasts a market peak of $50 billion outside the US, compared to $35 billion previously

It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability

Tirzepatide, the drug in Mounjaro, is a peptide with a molecular weight too high to be absorbed through the gut wall, even with the kind of absorption enhancer used to make oral semaglutide work

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