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Therefore, repeated-dose carnitine supplements only modestly increase the plasma L-carnitine concentration in muscular tissue even when very high oral doses are administrated, (i.e., more than 2 g per day) [14]
Safety varies by peptide type, source, dosage, and medical supervision
Hand Surg
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A Romanian randomized controlled trial including 62 VPA-poisoned patients admitted to the ICU (28 treated versus 34 non-treated patients with L-carnitine 1,800 mg/day for 3 days) reported that L-carnitine reduced plasma VPA levels and facilitated the decrease in plasma ammonia concentrations [27]