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Jaapa-Journal of the American Academy of Physician Assistants

1 For those taking Wegovy HD, 89% achieved 5% or greater body weight loss versus 38% taking placebo (from a baseline body weight of 248 lb.)

While some patients may continue Semaglutide after reaching their goal weight to maintain results, others may taper off

If glucose or weight-loss goals are not met on one GLP-1 agent at a therapeutic dose, the evidence-based approach is to optimize that single drug (titrate to effective dose, extend time on therapy) or switch to a different class entirelysuch as combining a GLP-1 with a SGLT2 inhibitor or adding metforminrather than stacking two GLP-1s

Hadavi, L

1 November 2004