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Semaglutide , administered once weekly at doses up to 2.4 mg for weight management, lists headache as a 'common' side effect in its SmPC

Their guidance states that patients taking oral medications should be aware that absorption rates may change and that monitoring for medication effectiveness and side effects should be increased during dose transitions

D3 inactivates both T4 and T3 but also increases rT3

Monami M, Marchionni N, Mannucci E

Wang, Q., Liu, Q., Wang, X., Zuo, Z., Oka, Y., and Lin, C