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After translocation from the endocytotic vesicle into the cytoplasm, the light chain proteolytically cleaves either SNAP-25 or synaptobrevin depending on the serological subtype of the neurotoxin

Specific supplementation of menaquinone-7-trans (K2, MK7-trans) could specifically target Matrix GLA protein function [316,317], but it is impractical on a clinical level, as low doses of MK-7 supplementation significantly influenced INR values (with a mean value of INR dropping by 40%) [332] (Table 2) (Figure 3)

Based on the submitted materials, we will try to verify as soon as possible

10.1016/j.phrs.2011.03.010 Pharmacol Res

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