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Gambini J, Ingls M, Olaso G, Lopez-Grueso R, Bonet-Costa V, Gimeno-Mallench L, et al
Mechanism of Action Melanotan 1 has been investigated for its potent and selective agonism of the melanocortin 1 receptor (MC1R), a Gs-coupled GPCR expressed on melanocytes and other cell types
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Classically, this effect is attributed to the fact that the phosphate form of selenium, which is essential for some steps of the gene transcription for Se-GSH-Px synthesis, would be more readily available from selenite than from selenomethionine (Yasumoto et al., 1979
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