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Epidemiology of psoriasis in the Russian Federation according to the patient registry

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[1, 12, 13] In humans, oral rapamycin is often used in immunosuppressive protocols in transplant recipients to prevent organ rejection.[1416] In some cases, due to the mTOR pathways close association with insulin signaling, rapamycin treatment has resulted in derangements in glucose homeostasis.[17, 18] However, multiple studies have documented potential benefits of rapamycin treatment in the context of normative aging

Clinical research and translational applications Current trends in clinical trials for aging interventions Senolytic agents in the clinical stage Several promising strategies against aging have entered clinical trials with preliminary evidence of safety and efficacy in humans (Table 3)

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