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Male GLP-1Rknockout ( Glp-1r / ) animals and WT littermates ( Glp-1r +/+ ) (916 weeks of age, 2430 g) were developed in our laboratory and characterized previously (54)

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La obesidad contribuye al desarrollo de la AOS principalmente a travs del exceso de tejido adiposo que rodea la va area superior que puede causar estrechamiento de las vas respiratorias e incrementar su tendencia al colapso durante el sueo3