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IGF1 indirectly increases DNA repair by 50% through increasing the p53 dependence in the p21, while inhibition IGF1R by siRNA in human prostate cancer cells enhances the sensitivity of ionizing radiation to SSBs and DSBs (Clark et al., 2005)

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Researchers interested in cognitive aspects of mood disorders find Dihexa relevant because of its pronounced effects on learning and memory, functions consistently impaired in depression