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The strength of synchronized delivery strategy lies in its ability to consolidate multiple synergistic mechanisms into a single formulation, greatly simplifying the complexity of combination therapy while offering excellent targeting capability and immunostimulatory potential

348,349 It is also noteworthy that CTE can lead to atypical astrocyte responses that contribute to recurrent seizures

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Expert Opin Ther Targets 16(12):11891202 So JS, Hur KY, Tarrio M, Ruda V, Frank-Kamenetsky M, Fitzgerald K et al (2012) Silencing of lipid metabolism genes through IRE1alpha-mediated mRNA decay lowers plasma lipids in mice