Best for: GLP-1 users who need significant meal variety to stay consistent with eating and who are experienced enough with macro tracking to self-select appropriate meals from a large, varied menu
Compared with placebo, retatrutide led to 10 percentage points more weight loss with 4 mg, 16 points with 8 mg, and 17 points with 12 mg
However, compounded versions are not FDA-approved, and quality, safety, and effectiveness may differ from branded products
Semaglutide is entering phase 3 evaluation in patients with early AD (NCT04777396)
The full program enrolls more than 5,800 participants and is structured to give Eli Lilly parallel readouts across obesity, diabetes, cardiovascular disease, and sleep apnea
Animal studies have suggested that there are potential risks to using Ozempic around pregnancy