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These symptoms typically diminish as your body acclimates to the medication, usually within two to three weeks of consistent use

Nicholls SJ, Bhatt DL, Buse JB, Prato SD, Kahn SE, Lincoff AM, McGuire DK, Nauck MA, Nissen SE, Sattar N, et al

Protein kinase A mediates glucagon-like peptide 1-induced nitric oxide production and muscle microvascular recruitment

The company made this prediction on the timing of FDA approval as it announced top-line results of a Phase 3 study showing a nearly 16% overall weight loss over a 17-month period among people who have both Type 2 diabetes and obesity 1

2023 May;29(5):305-340 Byrne RA, Rossello X, Coughlan JJ, et al

PLoS Biol 18(1):e3000585 Boer GA, Hay DL, Tups A (2023) Obesity pharmacotherapy: incretin action in the central nervous system