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doi:10.1016/S0140-6736(64)90011-X 182

The hormone GLP-1 is naturally secreted by the gut after a meal

CERP4 The potential role of artificial intelligence in the translation of PROMs: a pilot study with the Dutch translation of the PROMIS Sexual Function and Satisfaction measures Lorynn Teela 1 , Tessa van Gastel 1 , Athanasios Angelakis 1 , Lotte Haverman 1 , Caroline Terwee 1 1 Amsterdam UMC, Amsterdam, Netherlands Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :CERP4 Aims Translation and linguistic validation of patient-reported outcome measures (PROMs) is a time-consuming and costly process

Consider waiting for retatrutide if: You have severe obesity (BMI 40) and specifically need the difference between 15% and 28%+ weight loss a gap that matters clinically when 15% still leaves you in a high-risk range

After a 36-week lead-in period with tirzepatide treatment, participants who continued on the compound for an additional 52 weeks achieved 25.8% total weight loss