Oxidative Medicine and Cellular Longevity Leitner DF, Siu Y, Korman A, Lin Z, Kanshin E, Friedman D, Devore S, Ueberheide B, Tsirigos A, Jones DR, Wisniewski T (2023) Metabolomic, proteomic, and transcriptomic changes in adults with epilepsy on modified Atkins diet
Several nonclinical studies using lean and DIO animal models consistently demonstrated reductions in food intake and body weight (84)
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Stadtman, E
Why these features matter clinically: Smaller cell size reduces first-pass lung trapping, meaning more cells reach targets like myocardial infarct zones or cortical and subcortical neural regions