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Evidence continues to grow around their long-term health benefitsincluding improved cardiovascular outcomes, protection for the liver and kidneys, and reduced severity of sleep apnea

The mechanism combines the GLP-1 effects I already described with the additional insulin-stimulating and gastric-slowing effects of GIP

To identify any potential health risks or contraindications

& Chuen Li, S

A few GLP-1 agonists currently in phase 3 trials are higher-dose injectable semaglutide 7.2 mg (Novo Nordisk), oral semaglutide 50 mg (Novo Nordisk) and orforglipron (Eli Lilly)

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