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Treat 100 mcg as a modeling placeholder that makes the arithmetic concrete, not as evidence-based guidance

For the denominator definition for the mental health strata, we note that the principal diagnosis (first listed diagnosis at ED discharge), and not the patient disposition, would be used to define strata inclusion

Tachyphylaxis is contingent upon a full 24-hour exposure, as evidenced by a study in which rats treated with liraglutide (with half-life of 11 15 hours) twice daily for 14 days had markedly diminished gastric emptying while those treated with exenatide (with half-life of 2 3 hours) twice daily over the same period still displayed a profound reduction in gastric emptying, although both compounds had similar effects on body weight reduction (158)

This same mechanism drives weight loss

doi: 10.1371/journal.pone.0231136 389 NguyenTStainesDJohnstonSMarshall-GradisnikS

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