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Discard the pens after 28 days even if they are not expired

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As humas, when we age, cellular repair slows down, hydration levels decrease, oxidative stress increases, and essential nutrient absorption becomes less efficient

Finally, if the serum cobalamin concentration at the time of reevaluation is subnormal, further work-up is required to definitively diagnose the underlying disease process and cobalamin supplementation should be continued weekly or bi-weekly (for parenteral supplementation) or daily (for oral supplementation)