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It refers to blood loss to the optic nerve, which can lead to visual impairments and blindness

Sata, Antinociceptive effect of intrathecal administration of taurine in rat models of neuropathic pain, Can J Anaesth 58(7) (2011) 630-637

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Reproductive toxicity studies of acetylcysteine solution in the rat given oral doses of acetylcysteine solution up to 1,000 mg/kg (5.2 times the human mucolytic dose) have also been reported in the literature.1 The only adverse effect observed was a slight non-dose-related reduction in fertility at dose levels of 500 or 1,000 mg/kg/day (2.6 or 5.2 times the human mucolytic dose) in the Segment I study

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