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[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Greenberg AS, Egan JJ, Wek SA, Moos MC Jr., Londos C, Kimmel AR

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Nakagawa, T., Lomb, D

It has been studied for its role in supporting skin appearance and overall skin health for several decades in regenerative medicine literature

Vitamin B6 deficiency may lead to a variety of signs and symptoms, including skin rashes, mood changes, and low energy

A 2025 orthopaedic sports medicine systematic review describes increasing use despite lack of FDA approval and bans in sport, and emphasizes that the evidence base is dominated by preclinical studies with limited high-quality human data