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Translational in vivo and in vitro studies in patient (pts) with acute myeloid leukemia (AML), chronic myeloid leukemia (CML) and myeloproliferative disease (MPD) treated with MK-0457 (MK), a novel Aurora kinase, Flt3, JAK2, and Bcr-Abl inhibitor

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Ethics approval NESDAs research protocol was approved by the ethical review board of each participating research center in Amsterdam, Leiden, and Groningen (METC number 2003-183)

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Route of Administration: The Second Key Guideline The way B12 injections are given is very important