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Whether parallel alteration in platelet responsiveness and long-term thrombosis risk occurs in subjects remains to be determined, but as noted above, elevated serum levels of carnitine are associated with enhanced risks of major adverse cardiovascular events (6)

Quantifiable Fact: Early studies indicate similar rates of weight loss for some patients, though the extent of this similarity needs further investigation with larger, more controlled clinical trials

The study also identified factors associated with stopping and subsequently reinitiating including weight change the medications

Berberine studies suggest more modest effects, though direct head-to-head comparisons are lacking

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Most patients may experience gastrointestinal disturbances such as nausea, vomiting, diarrhea, and constipation