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They have an incretin action, reducing glucose plasmatic levels through the stimulation of insulin secretion by the pancreatic beta-cells and the concomitant inhibition of glucagon secretion by alpha-cells

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IS treatment was administered once weekly subcutaneously

J Hepatology 2016;64(2):S500

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Furthermore, 50 L of blood was taken from the submandibular vein and centrifuged at 4 C and 4,000 rpm for 20 min to collect plasma